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Under the Microscope: What Clinical Evidence Reveals About Modafinil Use in High-Stakes Professions

Under the Microscope: What Clinical Evidence Reveals About Modafinil Use in High-Stakes Professions

From military aviators to surgical residents, modafinil's off-label use as a cognitive enhancer in high-pressure professional settings has attracted substantial scientific scrutiny. A review of the available clinical trial data, occupational research, and regulatory guidance presents a nuanced picture — one that balances genuine performance benefits against important safety, ethical, and legal considerations.